March Madness 2025 Predictions And Odds. Here are the latest 2025 march madness odds, where the duke blue devils and uconn huskies are early favorites at u.s. 2025 ncaa tournament national title tiers:

Those odds imply a win probability of 16.67%. The duke blue devils are the opening favorites to win the 2025 ncaa tournament, with odds ranging from +1000 to +1200.